Miniprotein quick-otter-lotus

Type

Miniprotein

Binding

TREM2

Medium

Expressed

Yes

Ref

23_EuroBros_AF_Hallucination_ProteinMPNN_Pyrosetta_Boltz2

Collections

Sequence (65 AA)

SEAELEELKKKLVEEMMEQVRNYFKENPYDANHTRKLSPEEIEKVIEAAKEHVEKMVEKYLEHMT

Design Class

Miniprotein

Isoelectric Point

5.05pH

Molecular Weight

7850.84Da

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Binding

Yes

Binding Strength

Medium

5.3e-7M

Kon

6.2e+4M-1s-1

Koff

3.3e-2s-1

Kinetic Curves (SPR)

Concentration

10.0 nM

31.6 nM

100 nM

316 nM

1000 nM

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This protein was designed using FFAlphaFold2 Hallucination

AF Hallucination + ProteinMPNN + Pyrosetta + Boltz2