Protein deep-bear-clay

Kai Yi / deep-bear-clay

Type

Other

Binding

RBX1

Medium

Expressed

Yes

Ref

rbx1_ab_l214_41708_l0_b3

Collections

K[GEM x Adaptyv: RBX1 Binder Design Competition] Submission 1

AGEM x Adaptyv RBX1 Binder Competition: Main Submissions

AGEM x Adaptyv: RBX1 Binder Design Competition - Results

Sequence (214 AA)

DRAALEALGKEVLERVKGLVDDLVKVMNDPDASRMEIAEAARKMVSETARIAGEYAAKIPAGSAPTAVDYRLYEEMMLGFLIGVTVRVILEKEGYGLAPTAEEVRGFVTNFTRWMKRFPALPRKYLAKAAVIVRWTVRQVPLEGSGLTEEEIRELSEGFPASFGIDIETDPEVKVIIHELVTNVPEELKEAQKEFPLIKDFYDYLRELLKKIES

Computational Metrics

Experimental Metrics

Design Class

Other

Isoelectric Point

5.01pH

Molecular Weight

2.41e+4Da

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Binding

Yes

Binding Strength

Medium

8.5e-8M

Kon

5.2e+4M-1s-1

Koff

4.5e-3s-1

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Kinetic Curves (SPR)

Concentration

10.0 nM

31.6 nM

100 nM

316 nM

1000 nM

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Design Method

This protein was designed using KYAF2 Hallucination with ADFlip