Submission 1

zl-li/Submission 1

Description

We took into account the known target and published neutralizing antibody epitopes, and, guided by the scores from the binder design algorithm, selected multiple hotspots, including both the binding pocket and the neutralizing antibody epitopes located at the N terminus.

Proteins (10)

TableGrid

Zzl-li

id: steady-mole-ash

Binder

Other

PXDesign Server

Target

Nipah Virus Glycoprotein G

0.82

86.21

13.4 kDa

118

id: pale-fox-dust

Binder

Miniprotein

PXDesign Server

Target

Nipah Virus Glycoprotein G

0.78

92.23

7.8 kDa

id: vast-seal-frost

Binder

Miniprotein

PXDesign Server

Target

Nipah Virus Glycoprotein G

0.75

86.72

8.9 kDa

id: shy-quail-marble

Binder

Other

PXDesign Server

Target

Nipah Virus Glycoprotein G

0.74

89.39

16.1 kDa

147

id: gentle-owl-topaz

Binder

Miniprotein

PXDesign Server

Target

Nipah Virus Glycoprotein G

0.67

85.49

8.7 kDa

id: golden-lion-cypress

Binder

Other

PXDesign Server

Target

Nipah Virus Glycoprotein G

0.65

87.70

13.9 kDa

129

id: strong-jaguar-granite

Binder

Miniprotein

PXDesign Server

Target

Nipah Virus Glycoprotein G

0.61

89.30

8.7 kDa

id: ivory-heron-ember

Binder

Miniprotein

PXDesign Server

Target

Nipah Virus Glycoprotein G

0.51

86.25

9.0 kDa

id: bright-bear-clay

Binder

Miniprotein

PXDesign Server

Target

Nipah Virus Glycoprotein G

0.39

79.03

7.7 kDa

id: gentle-panther-onyx

Binder

Miniprotein

PXDesign Server

Target

Nipah Virus Glycoprotein G

0.01

86.97

8.6 kDa